Glutamate-rich protein 5 (ERICH5)
Homo sapiens — UniProt Q6P6B1
Data last refreshed: (UniProt release unknown)
Key facts
Glutamate-rich protein 5 (ERICH5) is a protein from Homo sapiens identified by UniProt accession Q6P6B1, 374 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q6P6B1; gene symbol ERICH5.
- Organism: Homo sapiens.
- Length: 374 amino acids.
- Top disease associations (Open Targets): PHF-tau measurement, colorectal adenocarcinoma and eosinophilic esophagitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glutamate-rich protein 5 |
|---|---|
| UniProt accession | Q6P6B1 |
| Gene | ERICH5 |
| Organism | Homo sapiens |
| Length | 374 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.21
- colorectal adenocarcinoma · score 0.04
- eosinophilic esophagitis · score 0.03
- blood protein measurement · score 0.03
- Down syndrome · score 0.03
- chronic interstitial cystitis · score 0.01
- nasopharyngeal neoplasm · score 0.01
- hepatocellular carcinoma · score 0.01
- squamous cell carcinoma · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P6B1-F1 | alphafold | PREDICTED | 48.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P6B1.
Amino-acid sequence (374 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ERICH5?
The strongest Open Targets associations for ERICH5 are PHF-tau measurement, colorectal adenocarcinoma, eosinophilic esophagitis, blood protein measurement and Down syndrome.
How long is the ERICH5 protein?
The Homo sapiens ERICH5 protein (UniProt Q6P6B1) is 374 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P6B1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P6B1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.