Ankyrin repeat domain-containing protein 16 (ANKRD16)
Homo sapiens — UniProt Q6P6B7
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 16 (ANKRD16) is a protein from Homo sapiens identified by UniProt accession Q6P6B7, 361 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q6P6B7; gene symbol ANKRD16.
- Organism: Homo sapiens.
- Length: 361 amino acids.
- Top disease associations (Open Targets): monocyte count, Eczematoid dermatitis and systemic lupus erythematosus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 16 |
|---|---|
| UniProt accession | Q6P6B7 |
| Gene | ANKRD16 |
| Organism | Homo sapiens |
| Length | 361 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.25
- Eczematoid dermatitis · score 0.21
- systemic lupus erythematosus · score 0.15
- myeloid white cell count · score 0.14
- monocyte percentage of leukocytes · score 0.12
- eosinophil count · score 0.11
- IGF-1 measurement · score 0.07
- leukocyte count · score 0.04
- blood protein measurement · score 0.04
- adolescent idiopathic scoliosis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P6B7-F1 | alphafold | PREDICTED | 93.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P6B7.
Amino-acid sequence (361 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD16?
The strongest Open Targets associations for ANKRD16 are monocyte count, Eczematoid dermatitis, systemic lupus erythematosus, myeloid white cell count and monocyte percentage of leukocytes.
How long is the ANKRD16 protein?
The Homo sapiens ANKRD16 protein (UniProt Q6P6B7) is 361 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P6B7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P6B7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.