Transmembrane protein 81 (TMEM81)
Homo sapiens — UniProt Q6P7N7
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 81 (TMEM81) is a protein from Homo sapiens identified by UniProt accession Q6P7N7, 255 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q6P7N7; gene symbol TMEM81.
- Organism: Homo sapiens.
- Length: 255 amino acids.
- Top disease associations (Open Targets): monocyte count, FEV/FVC ratio and Palmar Fibromatosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 81 |
|---|---|
| UniProt accession | Q6P7N7 |
| Gene | TMEM81 |
| Organism | Homo sapiens |
| Length | 255 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.29
- FEV/FVC ratio · score 0.28
- Palmar Fibromatosis · score 0.22
- basophil percentage of granulocytes · score 0.17
- protein measurement · score 0.16
- contactin-2 measurement · score 0.16
- red blood cell density measurement · score 0.15
- mathematical ability · score 0.14
- basophil count · score 0.14
- cutaneous melanoma · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P7N7-F1 | alphafold | PREDICTED | 84.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P7N7.
Amino-acid sequence (255 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM81?
The strongest Open Targets associations for TMEM81 are monocyte count, FEV/FVC ratio, Palmar Fibromatosis, basophil percentage of granulocytes and protein measurement.
How long is the TMEM81 protein?
The Homo sapiens TMEM81 protein (UniProt Q6P7N7) is 255 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P7N7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P7N7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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