Pyridoxal-dependent decarboxylase domain-containing protein 1 (PDXDC1)
Homo sapiens — UniProt Q6P996
Data last refreshed: (UniProt release unknown)
Key facts
Pyridoxal-dependent decarboxylase domain-containing protein 1 (PDXDC1) is a protein from Homo sapiens identified by UniProt accession Q6P996, 788 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.
- UniProt accession: Q6P996; gene symbol PDXDC1.
- Organism: Homo sapiens.
- Length: 788 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, phosphatidylcholine measurement and neuroinflammatory disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Pyridoxal-dependent decarboxylase domain-containing protein 1 |
|---|---|
| UniProt accession | Q6P996 |
| Gene | PDXDC1 |
| Organism | Homo sapiens |
| Length | 788 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (73)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.37
- phosphatidylcholine measurement · score 0.33
- neuroinflammatory disorder · score 0.33
- omega-6 polyunsaturated fatty acid measurement · score 0.30
- sex hormone-binding globulin measurement · score 0.27
- appendicular lean mass · score 0.27
- blood metabolite measurement · score 0.26
- body mass index · score 0.26
- alkaline phosphatase measurement · score 0.26
- high density lipoprotein cholesterol measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P996-F1 | alphafold | PREDICTED | 74.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P996.
Amino-acid sequence (788 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PDXDC1?
The strongest Open Targets associations for PDXDC1 are triglyceride measurement, phosphatidylcholine measurement, neuroinflammatory disorder, omega-6 polyunsaturated fatty acid measurement and sex hormone-binding globulin measurement.
How long is the PDXDC1 protein?
The Homo sapiens PDXDC1 protein (UniProt Q6P996) is 788 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P996 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P996 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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