Cytochrome b5 domain-containing protein 1 (CYB5D1)

About Cytochrome b5 domain-containing protein 1

Cytochrome b5 domain-containing protein 1 (CYB5D1) is a protein from Homo sapiens identified by UniProt accession Q6P9G0, 228 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	Cytochrome b5 domain-containing protein 1
UniProt accession	Q6P9G0
Gene	CYB5D1
Organism	Homo sapiens
Length	228 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (36)

Diseases linked to this target (Open Targets).

heel bone mineral density · score 0.15
diastolic blood pressure · score 0.12
mean reticulocyte volume · score 0.11
body height · score 0.10
neutrophil count · score 0.09
hypertension · score 0.09
urate measurement · score 0.09
mean platelet volume · score 0.09
platelet crit · score 0.06
bone quantitative ultrasound measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6P9G0-F1	alphafold	PREDICTED	86.76	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P9G0.

Amino-acid sequence (228 residues)

MPRRGLVAGP DLEYFQRRYF TPAEVAQHNR PEDLWVSYLG RVYDLTSLAQ EYKGNLLLKP IVEVAGQDIS HWFDPKTRDI RKHIDPLTGC LRYCTPRGRF VHVPPQLPCS DWANDFGKPW WQGSYYEVGR LSAKTRSIRI INTLTSQEHT LEVGVLESIW EILHRYLPYN SHAASYTWKY EGKNLNMDFT LEENGIRDEE EEFDYLSMDG TLHTPAILLY FNDDLTEL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards