GTPase IMAP family member 6 (GIMAP6)
Homo sapiens — UniProt Q6P9H5
Data last refreshed: (UniProt release unknown)
Key facts
GTPase IMAP family member 6 (GIMAP6) is a protein from Homo sapiens identified by UniProt accession Q6P9H5, 292 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.
- UniProt accession: Q6P9H5; gene symbol GIMAP6.
- Organism: Homo sapiens.
- Length: 292 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, C-reactive protein measurement and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GTPase IMAP family member 6 |
|---|---|
| UniProt accession | Q6P9H5 |
| Gene | GIMAP6 |
| Organism | Homo sapiens |
| Length | 292 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (110)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.31
- C-reactive protein measurement · score 0.26
- lymphocyte count · score 0.24
- lymphocyte percentage of leukocytes · score 0.14
- fibrinogen measurement · score 0.12
- triglyceride measurement · score 0.11
- Oral ulcer · score 0.10
- neutrophil percentage of leukocytes · score 0.10
- von Willebrand factor measurement · score 0.09
- hepatocellular carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P9H5-F1 | alphafold | PREDICTED | 86.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P9H5.
Amino-acid sequence (292 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GIMAP6?
The strongest Open Targets associations for GIMAP6 are high density lipoprotein cholesterol measurement, C-reactive protein measurement, lymphocyte count, lymphocyte percentage of leukocytes and fibrinogen measurement.
How long is the GIMAP6 protein?
The Homo sapiens GIMAP6 protein (UniProt Q6P9H5) is 292 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P9H5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P9H5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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