Protein FAM199X (FAM199X)
Homo sapiens — UniProt Q6PEV8
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM199X (FAM199X) is a protein from Homo sapiens identified by UniProt accession Q6PEV8, 388 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q6PEV8; gene symbol FAM199X.
- Organism: Homo sapiens.
- Length: 388 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, 15q11q13 microduplication syndrome and isolated asymptomatic elevation of creatine phosphokinase.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM199X |
|---|---|
| UniProt accession | Q6PEV8 |
| Gene | FAM199X |
| Organism | Homo sapiens |
| Length | 388 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- 15q11q13 microduplication syndrome · score 0.12
- isolated asymptomatic elevation of creatine phosphokinase · score 0.05
- pentosuria · score 0.04
- 46,XX ovotesticular disorder of sex development · score 0.03
- 46,XY complete gonadal dysgenesis · score 0.03
- meningococcal infection · score 0.00
- type 1 diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PEV8-F1 | alphafold | PREDICTED | 56.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PEV8.
Amino-acid sequence (388 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM199X?
The strongest Open Targets associations for FAM199X are neurodegenerative disease, 15q11q13 microduplication syndrome, isolated asymptomatic elevation of creatine phosphokinase, pentosuria and 46,XX ovotesticular disorder of sex development.
How long is the FAM199X protein?
The Homo sapiens FAM199X protein (UniProt Q6PEV8) is 388 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PEV8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PEV8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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