Protein FAM199X (FAM199X)

About Protein FAM199X

Protein FAM199X (FAM199X) is a protein from Homo sapiens identified by UniProt accession Q6PEV8, 388 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Protein FAM199X
UniProt accession	Q6PEV8
Gene	FAM199X
Organism	Homo sapiens
Length	388 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.52
15q11q13 microduplication syndrome · score 0.12
isolated asymptomatic elevation of creatine phosphokinase · score 0.05
pentosuria · score 0.04
46,XX ovotesticular disorder of sex development · score 0.03
46,XY complete gonadal dysgenesis · score 0.03
meningococcal infection · score 0.00
type 1 diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6PEV8-F1	alphafold	PREDICTED	56.29	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PEV8.

Amino-acid sequence (388 residues)

MSDEASAITS YEKFLTPEEP FPLLGPPRGV GTCPSEEPGC LDISDFGCQL SSCHRTDPLH RFHTNRWNLT SCGTSVASSE GSEELFSSVS VGDQDDCYSL LDDQDFTSFD LFPEGSVCSD VSSSISTYWD WSDSEFEWQL PGSDIASGSD VLSDVIPSIP SSPCLLPKKK NKHRNLDELP WSAMTNDEQV EYIEYLSRKV STEMGLREQL DIIKIIDPSA QISPTDSEFI IELNCLTDEK LKQVRNYIKE HSPRQRPARE AWKRSNFSCA STSGVSGASA SASSSSASMV SSASSSGSSV GNSASNSSAN MSRAHSDSNL SASAAERIRD SKKRSKQRKL QQKAFRKRQL KEQRQARKER LSGLFLNEEV LSLKVTEEDH EADVDVLM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards