Transmembrane protein 88 (TMEM88)
Homo sapiens — UniProt Q6PEY1
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 88 (TMEM88) is a protein from Homo sapiens identified by UniProt accession Q6PEY1, 159 residues long. MolForge cross-references it against 0 known binders and 112 disease associations.
- UniProt accession: Q6PEY1; gene symbol TMEM88.
- Organism: Homo sapiens.
- Length: 159 amino acids.
- Top disease associations (Open Targets): platelet count, platelet crit and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 88 |
|---|---|
| UniProt accession | Q6PEY1 |
| Gene | TMEM88 |
| Organism | Homo sapiens |
| Length | 159 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (112)
Diseases linked to this target (Open Targets).
- platelet count · score 0.18
- platelet crit · score 0.13
- body height · score 0.13
- reticulocyte count · score 0.10
- reticulocyte measurement · score 0.10
- neoplasm · score 0.08
- hepatocellular carcinoma · score 0.08
- non-small cell lung carcinoma · score 0.08
- erythrocyte count · score 0.08
- leukocyte count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PEY1-F1 | alphafold | PREDICTED | 69.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PEY1.
Amino-acid sequence (159 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM88?
The strongest Open Targets associations for TMEM88 are platelet count, platelet crit, body height, reticulocyte count and reticulocyte measurement.
How long is the TMEM88 protein?
The Homo sapiens TMEM88 protein (UniProt Q6PEY1) is 159 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PEY1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PEY1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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