Podocan-like protein 1 (PODNL1)
Homo sapiens — UniProt Q6PEZ8
Data last refreshed: (UniProt release unknown)
Key facts
Podocan-like protein 1 (PODNL1) is a protein from Homo sapiens identified by UniProt accession Q6PEZ8, 505 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q6PEZ8; gene symbol PODNL1.
- Organism: Homo sapiens.
- Length: 505 amino acids.
- Top disease associations (Open Targets): blood protein measurement, cancer and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Podocan-like protein 1 |
|---|---|
| UniProt accession | Q6PEZ8 |
| Gene | PODNL1 |
| Organism | Homo sapiens |
| Length | 505 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.08
- cancer · score 0.08
- neoplasm · score 0.06
- bladder transitional cell carcinoma · score 0.02
- gonorrhea · score 0.01
- Crohn's disease · score 0.01
- urinary bladder carcinoma · score 0.01
- glioblastoma multiforme · score 0.01
- lung adenocarcinoma · score 0.01
- lymphoid neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PEZ8-F1 | alphafold | PREDICTED | 86.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PEZ8.
Amino-acid sequence (505 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PODNL1?
The strongest Open Targets associations for PODNL1 are blood protein measurement, cancer, neoplasm, bladder transitional cell carcinoma and gonorrhea.
How long is the PODNL1 protein?
The Homo sapiens PODNL1 protein (UniProt Q6PEZ8) is 505 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PEZ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PEZ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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