Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 (PPIP5K1)
Homo sapiens — UniProt Q6PFW1
Data last refreshed: (UniProt release unknown)
Key facts
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 (PPIP5K1) is a protein from Homo sapiens identified by UniProt accession Q6PFW1, 1433 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q6PFW1; gene symbol PPIP5K1.
- Organism: Homo sapiens.
- Length: 1433 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, endometrial cancer and age at menopause.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 |
|---|---|
| UniProt accession | Q6PFW1 |
| Gene | PPIP5K1 |
| Organism | Homo sapiens |
| Length | 1433 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- endometrial cancer · score 0.18
- age at menopause · score 0.03
- cancer biomarker measurement · score 0.03
- mean corpuscular volume · score 0.02
- mathematical ability · score 0.02
- Obesity · score 0.02
- testosterone measurement · score 0.02
- platelet count · score 0.02
- diastolic blood pressure · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PFW1-F1 | alphafold | PREDICTED | 64.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PFW1.
Amino-acid sequence (1433 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPIP5K1?
The strongest Open Targets associations for PPIP5K1 are neurodegenerative disease, endometrial cancer, age at menopause, cancer biomarker measurement and mean corpuscular volume.
How long is the PPIP5K1 protein?
The Homo sapiens PPIP5K1 protein (UniProt Q6PFW1) is 1433 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PFW1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PFW1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.