Proline/serine-rich coiled-coil protein 1 (PSRC1)
Homo sapiens — UniProt Q6PGN9
Data last refreshed: (UniProt release unknown)
Key facts
Proline/serine-rich coiled-coil protein 1 (PSRC1) is a protein from Homo sapiens identified by UniProt accession Q6PGN9, 363 residues long. MolForge cross-references it against 0 known binders and 124 disease associations.
- UniProt accession: Q6PGN9; gene symbol PSRC1.
- Organism: Homo sapiens.
- Length: 363 amino acids.
- Top disease associations (Open Targets): coronary artery disease, low density lipoprotein cholesterol measurement and total cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Proline/serine-rich coiled-coil protein 1 |
|---|---|
| UniProt accession | Q6PGN9 |
| Gene | PSRC1 |
| Organism | Homo sapiens |
| Length | 363 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (124)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.34
- low density lipoprotein cholesterol measurement · score 0.33
- total cholesterol measurement · score 0.32
- blood protein measurement · score 0.31
- serum metabolite measurement · score 0.28
- myocardial infarction · score 0.27
- neurodegenerative disease · score 0.27
- drug use measurement · score 0.26
- serum alanine aminotransferase measurement · score 0.26
- high density lipoprotein cholesterol measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PGN9-F1 | alphafold | PREDICTED | 57.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PGN9.
Amino-acid sequence (363 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PSRC1?
The strongest Open Targets associations for PSRC1 are coronary artery disease, low density lipoprotein cholesterol measurement, total cholesterol measurement, blood protein measurement and serum metabolite measurement.
How long is the PSRC1 protein?
The Homo sapiens PSRC1 protein (UniProt Q6PGN9) is 363 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PGN9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PGN9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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