Solute carrier family 23 member 3 (SLC23A3)

Homo sapiens — UniProt Q6PIS1

Gene: SLC23A3Homo sapiensSwissProt reviewed

About Solute carrier family 23 member 3

Solute carrier family 23 member 3 (SLC23A3) is a protein from Homo sapiens identified by UniProt accession Q6PIS1, 610 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein nameSolute carrier family 23 member 3
UniProt accessionQ6PIS1
GeneSLC23A3
OrganismHomo sapiens
Length610 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (44)

Diseases linked to this target (Open Targets).

  • vitamin C measurement · score 0.20
  • leukocyte count · score 0.17
  • mean corpuscular volume · score 0.16
  • myeloid white cell count · score 0.15
  • body height · score 0.15
  • neutrophil count · score 0.14
  • mean corpuscular hemoglobin concentration · score 0.12
  • platelet count · score 0.12
  • mean corpuscular hemoglobin · score 0.11
  • grip strength measurement · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6PIS1-F1alphafoldPREDICTED75.90—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PIS1.

Amino-acid sequence (610 residues)

MSRSPLNPSQ LRSVGSQDAL APLPPPAPQN PSTHSWDPLC GSLPWGLSCL LALQHVLVMA SLLCVSHLLL LCSLSPGGLS YSPSQLLASS FFSCGMSTIL QTWMGSRLPL VQAPSLEFLI PALVLTSQKL PRAIQTPGNS SLMLHLCRGP SCHGLGHWNT SLQEVSGAVV VSGLLQGMMG LLGSPGHVFP HCGPLVLAPS LVVAGLSAHR EVAQFCFTHW GLALLVILLM VVCSQHLGSC QFHVCPWRRA STSSTHTPLP VFRLLSVLIP VACVWIVSAF VGFSVIPQEL SAPTKAPWIW LPHPGEWNWP LLTPRALAAG ISMALAASTS SLGCYALCGR LLHLPPPPPH ACSRGLSLEG LGSVLAGLLG SPMGTASSFP NVGKVGLIQA GSQQVAHLVG LLCVGLGLSP RLAQLLTTIP LPVVGGVLGV TQAVVLSAGF SSFYLADIDS GRNIFIVGFS IFMALLLPRW FREAPVLFST GWSPLDVLLH SLLTQPIFLA GLSGFLLENT IPGTQLERGL GQGLPSPFTA QEARMPQKPR EKAAQVYRLP FPIQNLCPCI PQPLHCLCPL PEDPGDEEGG SSEPEEMADL LPGSGEPCPE SSREGFRSQK

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Quick facts

UniProtQ6PIS1
GeneSLC23A3
OrganismHomo sapiens
Length610
Binders0
Diseases44
View on UniProt