POM121 and ZP3 fusion protein (POMZP3)
Homo sapiens — UniProt Q6PJE2
Data last refreshed: (UniProt release unknown)
Key facts
POM121 and ZP3 fusion protein (POMZP3) is a protein from Homo sapiens identified by UniProt accession Q6PJE2, 187 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q6PJE2; gene symbol POMZP3.
- Organism: Homo sapiens.
- Length: 187 amino acids.
- Top disease associations (Open Targets): Sepsis, puerperal disorder and adolescent idiopathic scoliosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | POM121 and ZP3 fusion protein |
|---|---|
| UniProt accession | Q6PJE2 |
| Gene | POMZP3 |
| Organism | Homo sapiens |
| Length | 187 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- Sepsis · score 0.31
- puerperal disorder · score 0.31
- adolescent idiopathic scoliosis · score 0.18
- CCL24 measurement · score 0.16
- refractive error measurement · score 0.15
- primary ovarian insufficiency · score 0.08
- 46,XX gonadal dysgenesis · score 0.07
- Female infertility due to fertilization defect · score 0.07
- 46,XY complete gonadal dysgenesis · score 0.06
- 46,XX testicular disorder of sex development · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PJE2-F1 | alphafold | PREDICTED | 73.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PJE2.
Amino-acid sequence (187 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with POMZP3?
The strongest Open Targets associations for POMZP3 are Sepsis, puerperal disorder, adolescent idiopathic scoliosis, CCL24 measurement and refractive error measurement.
How long is the POMZP3 protein?
The Homo sapiens POMZP3 protein (UniProt Q6PJE2) is 187 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PJE2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PJE2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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