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Mitotic deacetylase-associated SANT domain protein (MIDEAS)

Homo sapiens — UniProt Q6PJG2

Gene: MIDEASHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Mitotic deacetylase-associated SANT domain protein (MIDEAS) is a protein from Homo sapiens identified by UniProt accession Q6PJG2, 1045 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

  • UniProt accession: Q6PJG2; gene symbol MIDEAS.
  • Organism: Homo sapiens.
  • Length: 1045 amino acids.
  • Top disease associations (Open Targets): sex hormone-binding globulin measurement, high density lipoprotein cholesterol measurement and reticulocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameMitotic deacetylase-associated SANT domain protein
UniProt accessionQ6PJG2
GeneMIDEAS
OrganismHomo sapiens
Length1045 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (38)

Diseases linked to this target (Open Targets).

  • sex hormone-binding globulin measurement · score 0.47
  • high density lipoprotein cholesterol measurement · score 0.46
  • reticulocyte count · score 0.46
  • mean corpuscular volume · score 0.46
  • mean corpuscular hemoglobin concentration · score 0.45
  • mean corpuscular hemoglobin · score 0.43
  • apolipoprotein A 1 measurement · score 0.43
  • reticulocyte measurement · score 0.43
  • Red cell distribution width · score 0.42
  • hemoglobin measurement · score 0.41

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6PJG2-F1alphafoldPREDICTED48.35—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PJG2.

Amino-acid sequence (1045 residues)

MNLQAQPKAQ NKRKRCLFGG QEPAPKEQPP PLQPPQQSIR VKEEQYLGHE GPGGAVSTSQ PVELPPPSSL ALLNSVVYGP ERTSAAMLSQ QVASVKWPNS VMAPGRGPER GGGGGVSDSS WQQQPGQPPP HSTWNCHSLS LYSATKGSPH PGVGVPTYYN HPEALKREKA GGPQLDRYVR PMMPQKVQLE VGRPQAPLNS FHAAKKPPNQ SLPLQPFQLA FGHQVNRQVF RQGPPPPNPV AAFPPQKQQQ QQQPQQQQQQ QQAALPQMPL FENFYSMPQQ PSQQPQDFGL QPAGPLGQSH LAHHSMAPYP FPPNPDMNPE LRKALLQDSA PQPALPQVQI PFPRRSRRLS KEGILPPSAL DGAGTQPGQE ATGNLFLHHW PLQQPPPGSL GQPHPEALGF PLELRESQLL PDGERLAPNG REREAPAMGS EEGMRAVSTG DCGQVLRGGV IQSTRRRRRA SQEANLLTLA QKAVELASLQ NAKDGSGSEE KRKSVLASTT KCGVEFSEPS LATKRAREDS GMVPLIIPVS VPVRTVDPTE AAQAGGLDED GKGPEQNPAE HKPSVIVTRR RSTRIPGTDA QAQAEDMNVK LEGEPSVRKP KQRPRPEPLI IPTKAGTFIA PPVYSNITPY QSHLRSPVRL ADHPSERSFE LPPYTPPPIL SPVREGSGLY FNAIISTSTI PAPPPITPKS AHRTLLRTNS AEVTPPVLSV MGEATPVSIE PRINVGSRFQ AEIPLMRDRA LAAADPHKAD LVWQPWEDLE SSREKQRQVE DLLTAACSSI FPGAGTNQEL ALHCLHESRG DILETLNKLL LKKPLRPHNH PLATYHYTGS DQWKMAERKL FNKGIAIYKK DFFLVQKLIQ TKTVAQCVEF YYTYKKQVKI GRNGTLTFGD VDTSDEKSAQ EEVEVDIKTS QKFPRVPLPR RESPSEERLE PKREVKEPRK EGEEEVPEIQ EKEEQEEGRE RSRRAAAVKA TQTLQANESA SDILILRSHE SNAPGSAGGQ ASEKPREGTG KSRRALPFSE KKKKTETFSK TQNQENTFPC KKCGR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with MIDEAS?

The strongest Open Targets associations for MIDEAS are sex hormone-binding globulin measurement, high density lipoprotein cholesterol measurement, reticulocyte count, mean corpuscular volume and mean corpuscular hemoglobin concentration.

How long is the MIDEAS protein?

The Homo sapiens MIDEAS protein (UniProt Q6PJG2) is 1045 amino acids long.

Browse: Targets: M · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6PJG2
GeneMIDEAS
OrganismHomo sapiens
Length1045
Binders0
Diseases38
View on UniProt