Forkhead box protein R2 (FOXR2)
Homo sapiens — UniProt Q6PJQ5
Data last refreshed: (UniProt release unknown)
Key facts
Forkhead box protein R2 (FOXR2) is a protein from Homo sapiens identified by UniProt accession Q6PJQ5, 311 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q6PJQ5; gene symbol FOXR2.
- Organism: Homo sapiens.
- Length: 311 amino acids.
- Top disease associations (Open Targets): neoplasm, neuroblastoma and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Forkhead box protein R2 |
|---|---|
| UniProt accession | Q6PJQ5 |
| Gene | FOXR2 |
| Organism | Homo sapiens |
| Length | 311 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.10
- neuroblastoma · score 0.08
- cancer · score 0.08
- urinary bladder carcinoma · score 0.05
- esophageal adenocarcinoma · score 0.05
- non-small cell lung carcinoma · score 0.03
- malignant peripheral nerve sheath tumor · score 0.03
- hepatocellular carcinoma · score 0.02
- glioblastoma · score 0.02
- triple-negative breast cancer · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PJQ5-F1 | alphafold | PREDICTED | 64.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PJQ5.
Amino-acid sequence (311 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FOXR2?
The strongest Open Targets associations for FOXR2 are neoplasm, neuroblastoma, cancer, urinary bladder carcinoma and esophageal adenocarcinoma.
How long is the FOXR2 protein?
The Homo sapiens FOXR2 protein (UniProt Q6PJQ5) is 311 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PJQ5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PJQ5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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