Zinc finger CCCH domain-containing protein 14 (ZC3H14)
Homo sapiens — UniProt Q6PJT7
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger CCCH domain-containing protein 14 (ZC3H14) is a protein from Homo sapiens identified by UniProt accession Q6PJT7, 736 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.
- UniProt accession: Q6PJT7; gene symbol ZC3H14.
- Organism: Homo sapiens.
- Length: 736 amino acids.
- Top disease associations (Open Targets): intellectual disability, autosomal recessive 56, autosomal recessive non-syndromic intellectual disability and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger CCCH domain-containing protein 14 |
|---|---|
| UniProt accession | Q6PJT7 |
| Gene | ZC3H14 |
| Organism | Homo sapiens |
| Length | 736 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (70)
Diseases linked to this target (Open Targets).
- intellectual disability, autosomal recessive 56 · score 0.51
- autosomal recessive non-syndromic intellectual disability · score 0.37
- Intellectual disability · score 0.22
- body height · score 0.12
- chronotype measurement · score 0.08
- kynurenine measurement · score 0.08
- Fuchs endothelial corneal dystrophy · score 0.07
- X-linked endothelial corneal dystrophy · score 0.06
- tauopathy · score 0.06
- granular corneal dystrophy type I · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PJT7-F1 | alphafold | PREDICTED | 56.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PJT7.
Amino-acid sequence (736 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZC3H14?
The strongest Open Targets associations for ZC3H14 are intellectual disability, autosomal recessive 56, autosomal recessive non-syndromic intellectual disability, Intellectual disability, body height and chronotype measurement.
How long is the ZC3H14 protein?
The Homo sapiens ZC3H14 protein (UniProt Q6PJT7) is 736 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PJT7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PJT7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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