Consortin (CNST)
Homo sapiens — UniProt Q6PJW8
Data last refreshed: (UniProt release unknown)
Key facts
Consortin (CNST) is a protein from Homo sapiens identified by UniProt accession Q6PJW8, 725 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q6PJW8; gene symbol CNST.
- Organism: Homo sapiens.
- Length: 725 amino acids.
- Top disease associations (Open Targets): acute myeloid leukemia, hemolysis and osteosarcoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Consortin |
|---|---|
| UniProt accession | Q6PJW8 |
| Gene | CNST |
| Organism | Homo sapiens |
| Length | 725 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- acute myeloid leukemia · score 0.07
- hemolysis · score 0.06
- osteosarcoma · score 0.03
- neoplasm · score 0.01
- Alzheimer disease · score 0.01
- Ataxia-telangiectasia · score 0.01
- lymph node metastatic carcinoma · score 0.01
- Lyme disease · score 0.01
- cancer · score 0.00
- Cataract · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PJW8-F1 | alphafold | PREDICTED | 52.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PJW8.
Amino-acid sequence (725 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNST?
The strongest Open Targets associations for CNST are acute myeloid leukemia, hemolysis, osteosarcoma, neoplasm and Alzheimer disease.
How long is the CNST protein?
The Homo sapiens CNST protein (UniProt Q6PJW8) is 725 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PJW8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PJW8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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