Coiled-coil domain-containing protein 137 (CCDC137)
Homo sapiens — UniProt Q6PK04
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 137 (CCDC137) is a protein from Homo sapiens identified by UniProt accession Q6PK04, 289 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q6PK04; gene symbol CCDC137.
- Organism: Homo sapiens.
- Length: 289 amino acids.
- Top disease associations (Open Targets): creatinine measurement, hepatocellular carcinoma and Age-related cataract.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 137 |
|---|---|
| UniProt accession | Q6PK04 |
| Gene | CCDC137 |
| Organism | Homo sapiens |
| Length | 289 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- creatinine measurement · score 0.18
- hepatocellular carcinoma · score 0.10
- Age-related cataract · score 0.09
- neoplasm · score 0.08
- total blood protein measurement · score 0.05
- cancer · score 0.05
- serum non-albumin protein measurement · score 0.04
- protein measurement · score 0.04
- mathematical ability · score 0.03
- monocyte percentage of leukocytes · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PK04-F1 | alphafold | PREDICTED | 73.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PK04.
Amino-acid sequence (289 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC137?
The strongest Open Targets associations for CCDC137 are creatinine measurement, hepatocellular carcinoma, Age-related cataract, neoplasm and total blood protein measurement.
How long is the CCDC137 protein?
The Homo sapiens CCDC137 protein (UniProt Q6PK04) is 289 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PK04 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PK04 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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