2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (OGFOD3)
Homo sapiens — UniProt Q6PK18
Data last refreshed: (UniProt release unknown)
Key facts
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (OGFOD3) is a protein from Homo sapiens identified by UniProt accession Q6PK18, 319 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q6PK18; gene symbol OGFOD3.
- Organism: Homo sapiens.
- Length: 319 amino acids.
- Top disease associations (Open Targets): blood protein measurement, platelet count and base metabolic rate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 |
|---|---|
| UniProt accession | Q6PK18 |
| Gene | OGFOD3 |
| Organism | Homo sapiens |
| Length | 319 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.34
- platelet count · score 0.05
- base metabolic rate measurement · score 0.05
- attention deficit hyperactivity disorder · score 0.04
- schizophrenia 15 · score 0.04
- metabolite measurement · score 0.03
- Phelan-McDermid syndrome · score 0.03
- monocyte percentage of leukocytes · score 0.02
- inherited lipid metabolism disorder · score 0.01
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PK18-F1 | alphafold | PREDICTED | 85.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PK18.
Amino-acid sequence (319 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OGFOD3?
The strongest Open Targets associations for OGFOD3 are blood protein measurement, platelet count, base metabolic rate measurement, attention deficit hyperactivity disorder and schizophrenia 15.
How long is the OGFOD3 protein?
The Homo sapiens OGFOD3 protein (UniProt Q6PK18) is 319 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PK18 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PK18 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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