La-related protein 1 (LARP1)
Homo sapiens — UniProt Q6PKG0
Data last refreshed: (UniProt release unknown)
Key facts
La-related protein 1 (LARP1) is a protein from Homo sapiens identified by UniProt accession Q6PKG0, 1096 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.
- UniProt accession: Q6PKG0; gene symbol LARP1.
- Organism: Homo sapiens.
- Length: 1096 amino acids.
- Top disease associations (Open Targets): mean corpuscular hemoglobin, Red cell distribution width and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | La-related protein 1 |
|---|---|
| UniProt accession | Q6PKG0 |
| Gene | LARP1 |
| Organism | Homo sapiens |
| Length | 1096 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (86)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin · score 0.46
- Red cell distribution width · score 0.45
- mean corpuscular hemoglobin concentration · score 0.44
- mean corpuscular volume · score 0.43
- erythrocyte count · score 0.36
- heel bone mineral density · score 0.35
- reticulocyte count · score 0.33
- hemoglobin measurement · score 0.31
- red blood cell density measurement · score 0.30
- reticulocyte measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PKG0-F1 | alphafold | PREDICTED | 53.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PKG0.
Amino-acid sequence (1096 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LARP1?
The strongest Open Targets associations for LARP1 are mean corpuscular hemoglobin, Red cell distribution width, mean corpuscular hemoglobin concentration, mean corpuscular volume and erythrocyte count.
How long is the LARP1 protein?
The Homo sapiens LARP1 protein (UniProt Q6PKG0) is 1096 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PKG0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PKG0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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