Docking protein 6 (DOK6)
Homo sapiens — UniProt Q6PKX4
Data last refreshed: (UniProt release unknown)
Key facts
Docking protein 6 (DOK6) is a protein from Homo sapiens identified by UniProt accession Q6PKX4, 331 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.
- UniProt accession: Q6PKX4; gene symbol DOK6.
- Organism: Homo sapiens.
- Length: 331 amino acids.
- Top disease associations (Open Targets): platelet component distribution width, insomnia and total blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Docking protein 6 |
|---|---|
| UniProt accession | Q6PKX4 |
| Gene | DOK6 |
| Organism | Homo sapiens |
| Length | 331 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (76)
Diseases linked to this target (Open Targets).
- platelet component distribution width · score 0.40
- insomnia · score 0.29
- total blood protein measurement · score 0.29
- myocardial infarction · score 0.28
- flatulence · score 0.26
- protein measurement · score 0.24
- thyroid gland adenocarcinoma · score 0.23
- genetic disorder · score 0.12
- mitochondrial DNA measurement · score 0.11
- mean platelet volume · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6PKX4-F1 | alphafold | PREDICTED | 73.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6PKX4.
Amino-acid sequence (331 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DOK6?
The strongest Open Targets associations for DOK6 are platelet component distribution width, insomnia, total blood protein measurement, myocardial infarction and flatulence.
How long is the DOK6 protein?
The Homo sapiens DOK6 protein (UniProt Q6PKX4) is 331 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6PKX4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6PKX4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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