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Aminopeptidase Q (LVRN)

Homo sapiens — UniProt Q6Q4G3

Gene: LVRNHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Aminopeptidase Q (LVRN) is a protein from Homo sapiens identified by UniProt accession Q6Q4G3, 990 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

  • UniProt accession: Q6Q4G3; gene symbol LVRN.
  • Organism: Homo sapiens.
  • Length: 990 amino acids.
  • Top disease associations (Open Targets): Red cell distribution width, mean corpuscular hemoglobin and intraocular pressure measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameAminopeptidase Q
UniProt accessionQ6Q4G3
GeneLVRN
OrganismHomo sapiens
Length990 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (29)

Diseases linked to this target (Open Targets).

  • Red cell distribution width · score 0.45
  • mean corpuscular hemoglobin · score 0.33
  • intraocular pressure measurement · score 0.30
  • mean corpuscular hemoglobin concentration · score 0.30
  • osteoarthritis, hand · score 0.28
  • musculoskeletal system disease · score 0.19
  • acute myeloid leukemia · score 0.09
  • myelodysplastic syndrome · score 0.07
  • neoplasm · score 0.05
  • non-small cell lung carcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6Q4G3-F1alphafoldPREDICTED88.64—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6Q4G3.

Amino-acid sequence (990 residues)

MGPPSSSGFY VSRAVALLLA GLVAALLLAL AVLAALYGHC ERVPPSELPG LRDLEAESSP PLRQKPTPTP KPSSARELAV TTTPSNWRPP GPWDQLRLPP WLVPLHYDLE LWPQLRPDEL PAGSLPFTGR VNITVRCTVA TSRLLLHSLF QDCERAEVRG PLSPGTGNAT VGRVPVDDVW FALDTEYMVL ELSEPLKPGS SYELQLSFSG LVKEDLREGL FLNVYTDQGE RRALLASQLE PTFARYVFPC FDEPALKATF NITMIHHPSY VALSNMPKLG QSEKEDVNGS KWTVTTFSTT PHMPTYLVAF VICDYDHVNR TERGKEIRIW ARKDAIANGS ADFALNITGP IFSFLEDLFN ISYSLPKTDI IALPSFDNHA MENWGLMIFD ESGLLLEPKD QLTEKKTLIS YVVSHEIGHQ WFGNLVTMNW WNNIWLNEGF ASYFEFEVIN YFNPKLPRNE IFFSNILHNI LREDHALVTR AVAMKVENFK TSEIQELFDI FTYSKGASMA RMLSCFLNEH LFVSALKSYL KTFSYSNAEQ DDLWRHFQMA IDDQSTVILP ATIKNIMDSW THQSGFPVIT LNVSTGVMKQ EPFYLENIKN RTLLTSNDTW IVPILWIKNG TTQPLVWLDQ SSKVFPEMQV SDSDHDWVIL NLNMTGYYRV NYDKLGWKKL NQQLEKDPKA IPVIHRLQLI DDAFSLSKNN YIEIETALEL TKYLAEEDEI IVWHTVLVNL VTRDLVSEVN IYDIYSLLKR YLLKRLNLIW NIYSTIIREN VLALQDDYLA LISLEKLFVT ACWLGLEDCL QLSKELFAKW VDHPENEIPY PIKDVVLCYG IALGSDKEWD ILLNTYTNTT NKEEKIQLAY AMSCSKDPWI LNRYMEYAIS TSPFTSNETN IIEVVASSEV GRYVAKDFLV NNWQAVSKRY GTQSLINLIY TIGRTVTTDL QIVELQQFFS NMLEEHQRIR VHANLQTIKN ENLKNKKLSA RIAAWLRRNT

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with LVRN?

The strongest Open Targets associations for LVRN are Red cell distribution width, mean corpuscular hemoglobin, intraocular pressure measurement, mean corpuscular hemoglobin concentration and osteoarthritis, hand.

How long is the LVRN protein?

The Homo sapiens LVRN protein (UniProt Q6Q4G3) is 990 amino acids long.

Browse: Targets: L · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6Q4G3
GeneLVRN
OrganismHomo sapiens
Length990
Binders0
Diseases29
View on UniProt