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Cysteine-rich protein 3 (CRIP3)

Homo sapiens — UniProt Q6Q6R5

Gene: CRIP3Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Cysteine-rich protein 3 (CRIP3) is a protein from Homo sapiens identified by UniProt accession Q6Q6R5, 217 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

  • UniProt accession: Q6Q6R5; gene symbol CRIP3.
  • Organism: Homo sapiens.
  • Length: 217 amino acids.
  • Top disease associations (Open Targets): urate measurement, neurodegenerative disease and systolic blood pressure.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCysteine-rich protein 3
UniProt accessionQ6Q6R5
GeneCRIP3
OrganismHomo sapiens
Length217 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (63)

Diseases linked to this target (Open Targets).

  • urate measurement · score 0.32
  • neurodegenerative disease · score 0.31
  • systolic blood pressure · score 0.30
  • mean corpuscular volume · score 0.29
  • diastolic blood pressure · score 0.28
  • pulse pressure measurement · score 0.28
  • body height · score 0.27
  • serum urea measurement · score 0.27
  • BMI-adjusted waist-hip ratio · score 0.24
  • heel bone mineral density · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6Q6R5-F1alphafoldPREDICTED74.36—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6Q6R5.

Amino-acid sequence (217 residues)

MSWTCPRCQQ PVFFAEKVSS LGKNWHRFCL KCERCHSILS PGGHAEHNGR PYCHKPCYGA LFGPRGVNIG GVGSYLYNPP TPSPGCTTPL SPSSFSPPRP RTGLPQGKKS PPHMKTFTGE TSLCPGCGEP VYFAEKVMSL GRNWHRPCLR CQRCHKTLTA GSHAEHDGVP YCHVPCYGYL FGPKGGQPHP RHWDGMYMPE VWHVHGLWVC VDNFPCG

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CRIP3?

The strongest Open Targets associations for CRIP3 are urate measurement, neurodegenerative disease, systolic blood pressure, mean corpuscular volume and diastolic blood pressure.

How long is the CRIP3 protein?

The Homo sapiens CRIP3 protein (UniProt Q6Q6R5) is 217 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6Q6R5
GeneCRIP3
OrganismHomo sapiens
Length217
Binders0
Diseases63
View on UniProt