Cell surface glycoprotein CD200 receptor 2 (CD200R1L)
Homo sapiens — UniProt Q6Q8B3
Data last refreshed: (UniProt release unknown)
Key facts
Cell surface glycoprotein CD200 receptor 2 (CD200R1L) is a protein from Homo sapiens identified by UniProt accession Q6Q8B3, 271 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q6Q8B3; gene symbol CD200R1L.
- Organism: Homo sapiens.
- Length: 271 amino acids.
- Top disease associations (Open Targets): blood protein measurement, insomnia and total blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cell surface glycoprotein CD200 receptor 2 |
|---|---|
| UniProt accession | Q6Q8B3 |
| Gene | CD200R1L |
| Organism | Homo sapiens |
| Length | 271 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.33
- insomnia · score 0.31
- total blood protein measurement · score 0.31
- Eczematoid dermatitis · score 0.30
- eosinophil percentage of leukocytes · score 0.26
- cortisol measurement · score 0.26
- seasonal allergic rhinitis · score 0.24
- allergic rhinitis · score 0.24
- eosinophil count · score 0.20
- PHF-tau measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6Q8B3-F1 | alphafold | PREDICTED | 83.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6Q8B3.
Amino-acid sequence (271 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CD200R1L?
The strongest Open Targets associations for CD200R1L are blood protein measurement, insomnia, total blood protein measurement, Eczematoid dermatitis and eosinophil percentage of leukocytes.
How long is the CD200R1L protein?
The Homo sapiens CD200R1L protein (UniProt Q6Q8B3) is 271 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6Q8B3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6Q8B3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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