Coronin-6 (CORO6)
Homo sapiens — UniProt Q6QEF8
Data last refreshed: (UniProt release unknown)
Key facts
Coronin-6 (CORO6) is a protein from Homo sapiens identified by UniProt accession Q6QEF8, 472 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q6QEF8; gene symbol CORO6.
- Organism: Homo sapiens.
- Length: 472 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, neuroimaging measurement and coronary artery disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coronin-6 |
|---|---|
| UniProt accession | Q6QEF8 |
| Gene | CORO6 |
| Organism | Homo sapiens |
| Length | 472 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.40
- neuroimaging measurement · score 0.36
- coronary artery disease · score 0.32
- brain volume measurement · score 0.30
- brain measurement · score 0.29
- cortical thickness · score 0.28
- neurodegenerative disease · score 0.28
- lymphocyte count · score 0.26
- bone quantitative ultrasound measurement · score 0.23
- erythrocyte count · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6QEF8-F1 | alphafold | PREDICTED | 91.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6QEF8.
Amino-acid sequence (472 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CORO6?
The strongest Open Targets associations for CORO6 are heel bone mineral density, neuroimaging measurement, coronary artery disease, brain volume measurement and brain measurement.
How long is the CORO6 protein?
The Homo sapiens CORO6 protein (UniProt Q6QEF8) is 472 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6QEF8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6QEF8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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