Adhesion G-protein coupled receptor D1 (ADGRD1)
Homo sapiens — UniProt Q6QNK2
Data last refreshed: (UniProt release unknown)
Key facts
Adhesion G-protein coupled receptor D1 (ADGRD1) is a protein from Homo sapiens identified by UniProt accession Q6QNK2, 874 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.
- UniProt accession: Q6QNK2; gene symbol ADGRD1.
- Organism: Homo sapiens.
- Length: 874 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, body height and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adhesion G-protein coupled receptor D1 |
|---|---|
| UniProt accession | Q6QNK2 |
| Gene | ADGRD1 |
| Organism | Homo sapiens |
| Length | 874 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (88)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.43
- body height · score 0.42
- appendicular lean mass · score 0.41
- blood phosphate measurement · score 0.38
- lean body mass · score 0.36
- nervous system disease · score 0.31
- sporadic amyotrophic lateral sclerosis · score 0.30
- RR interval · score 0.30
- sex hormone-binding globulin measurement · score 0.30
- BMI-adjusted waist-hip ratio · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6QNK2-F1 | alphafold | PREDICTED | 71.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6QNK2.
Amino-acid sequence (874 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADGRD1?
The strongest Open Targets associations for ADGRD1 are heel bone mineral density, body height, appendicular lean mass, blood phosphate measurement and lean body mass.
How long is the ADGRD1 protein?
The Homo sapiens ADGRD1 protein (UniProt Q6QNK2) is 874 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6QNK2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6QNK2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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