Biogenesis of lysosome-related organelles complex 1 subunit 3 (BLOC1S3)
Homo sapiens — UniProt Q6QNY0
Data last refreshed: (UniProt release unknown)
Key facts
Biogenesis of lysosome-related organelles complex 1 subunit 3 (BLOC1S3) is a protein from Homo sapiens identified by UniProt accession Q6QNY0, 202 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q6QNY0; gene symbol BLOC1S3.
- Organism: Homo sapiens.
- Length: 202 amino acids.
- Top disease associations (Open Targets): Hermansky-Pudlak syndrome 8, Hermansky-Pudlak syndrome and Hermansky-Pudlak syndrome type 7.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Biogenesis of lysosome-related organelles complex 1 subunit 3 |
|---|---|
| UniProt accession | Q6QNY0 |
| Gene | BLOC1S3 |
| Organism | Homo sapiens |
| Length | 202 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- Hermansky-Pudlak syndrome 8 · score 0.70
- Hermansky-Pudlak syndrome · score 0.48
- Hermansky-Pudlak syndrome type 7 · score 0.37
- Hermansky-Pudlak syndrome type 8 · score 0.37
- neurodegenerative disease · score 0.32
- calcium measurement · score 0.26
- mean platelet volume · score 0.24
- refractive error measurement · score 0.20
- hemoglobin measurement · score 0.19
- genetic disorder · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6QNY0-F1 | alphafold | PREDICTED | 71.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6QNY0.
Amino-acid sequence (202 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BLOC1S3?
The strongest Open Targets associations for BLOC1S3 are Hermansky-Pudlak syndrome 8, Hermansky-Pudlak syndrome, Hermansky-Pudlak syndrome type 7, Hermansky-Pudlak syndrome type 8 and neurodegenerative disease.
How long is the BLOC1S3 protein?
The Homo sapiens BLOC1S3 protein (UniProt Q6QNY0) is 202 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6QNY0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6QNY0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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