Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC1S2)
Homo sapiens — UniProt Q6QNY1
Data last refreshed: (UniProt release unknown)
Key facts
Biogenesis of lysosome-related organelles complex 1 subunit 2 (BLOC1S2) is a protein from Homo sapiens identified by UniProt accession Q6QNY1, 142 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.
- UniProt accession: Q6QNY1; gene symbol BLOC1S2.
- Organism: Homo sapiens.
- Length: 142 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, triglyceride measurement and intelligence.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Biogenesis of lysosome-related organelles complex 1 subunit 2 |
|---|---|
| UniProt accession | Q6QNY1 |
| Gene | BLOC1S2 |
| Organism | Homo sapiens |
| Length | 142 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- triglyceride measurement · score 0.13
- intelligence · score 0.09
- serum alanine aminotransferase measurement · score 0.08
- cognitive function measurement · score 0.07
- type 2 diabetes mellitus · score 0.07
- self reported educational attainment · score 0.07
- high density lipoprotein cholesterol measurement · score 0.07
- total cholesterol measurement · score 0.07
- creatine kinase measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6QNY1-F1 | alphafold | PREDICTED | 86.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6QNY1.
Amino-acid sequence (142 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BLOC1S2?
The strongest Open Targets associations for BLOC1S2 are neurodegenerative disease, triglyceride measurement, intelligence, serum alanine aminotransferase measurement and cognitive function measurement.
How long is the BLOC1S2 protein?
The Homo sapiens BLOC1S2 protein (UniProt Q6QNY1) is 142 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6QNY1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6QNY1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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