POTE ankyrin domain family member G (POTEG)
Homo sapiens — UniProt Q6S5H5
Data last refreshed: (UniProt release unknown)
Key facts
POTE ankyrin domain family member G (POTEG) is a protein from Homo sapiens identified by UniProt accession Q6S5H5, 508 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q6S5H5; gene symbol POTEG.
- Organism: Homo sapiens.
- Length: 508 amino acids.
- Top disease associations (Open Targets): esophageal squamous cell carcinoma, neoplasm and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | POTE ankyrin domain family member G |
|---|---|
| UniProt accession | Q6S5H5 |
| Gene | POTEG |
| Organism | Homo sapiens |
| Length | 508 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- esophageal squamous cell carcinoma · score 0.07
- neoplasm · score 0.06
- cancer · score 0.00
- lymph node metastatic carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6S5H5-F1 | alphafold | PREDICTED | 65.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6S5H5.
Amino-acid sequence (508 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with POTEG?
The strongest Open Targets associations for POTEG are esophageal squamous cell carcinoma, neoplasm, cancer and lymph node metastatic carcinoma.
How long is the POTEG protein?
The Homo sapiens POTEG protein (UniProt Q6S5H5) is 508 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6S5H5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6S5H5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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