POTE ankyrin domain family member E (POTEE)
Homo sapiens — UniProt Q6S8J3
Data last refreshed: (UniProt release unknown)
Key facts
POTE ankyrin domain family member E (POTEE) is a protein from Homo sapiens identified by UniProt accession Q6S8J3, 1075 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q6S8J3; gene symbol POTEE.
- Organism: Homo sapiens.
- Length: 1075 amino acids.
- Top disease associations (Open Targets): colorectal carcinoma, neoplasm and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | POTE ankyrin domain family member E |
|---|---|
| UniProt accession | Q6S8J3 |
| Gene | POTEE |
| Organism | Homo sapiens |
| Length | 1075 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- colorectal carcinoma · score 0.02
- neoplasm · score 0.02
- cancer · score 0.02
- carcinoma of liver and intrahepatic biliary tract · score 0.01
- lung adenocarcinoma · score 0.01
- colorectal neoplasm · score 0.01
- type 2 diabetes mellitus · score 0.00
- non-small cell lung carcinoma · score 0.00
- Ataxia-telangiectasia · score 0.00
- lumbar disc degeneration · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6S8J3-F1 | alphafold | PREDICTED | 70.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6S8J3.
Amino-acid sequence (1075 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with POTEE?
The strongest Open Targets associations for POTEE are colorectal carcinoma, neoplasm, cancer, carcinoma of liver and intrahepatic biliary tract and lung adenocarcinoma.
How long is the POTEE protein?
The Homo sapiens POTEE protein (UniProt Q6S8J3) is 1075 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6S8J3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6S8J3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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