Serine protease FAM111B (FAM111B)
Homo sapiens — UniProt Q6SJ93
Data last refreshed: (UniProt release unknown)
Key facts
Serine protease FAM111B (FAM111B) is a protein from Homo sapiens identified by UniProt accession Q6SJ93, 734 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q6SJ93; gene symbol FAM111B.
- Organism: Homo sapiens.
- Length: 734 amino acids.
- Top disease associations (Open Targets): hereditary sclerosing poikiloderma with tendon and pulmonary involvement, prostate carcinoma and myositis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine protease FAM111B |
|---|---|
| UniProt accession | Q6SJ93 |
| Gene | FAM111B |
| Organism | Homo sapiens |
| Length | 734 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- hereditary sclerosing poikiloderma with tendon and pulmonary involvement · score 0.70
- prostate carcinoma · score 0.28
- myositis · score 0.27
- Kyphosis · score 0.27
- Short stature · score 0.27
- neurodegenerative disease · score 0.26
- sex hormone-binding globulin measurement · score 0.21
- genetic disorder · score 0.19
- lung adenocarcinoma · score 0.10
- neoplasm · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6SJ93-F1 | alphafold | PREDICTED | 69.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6SJ93.
Amino-acid sequence (734 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM111B?
The strongest Open Targets associations for FAM111B are hereditary sclerosing poikiloderma with tendon and pulmonary involvement, prostate carcinoma, myositis, Kyphosis and Short stature.
How long is the FAM111B protein?
The Homo sapiens FAM111B protein (UniProt Q6SJ93) is 734 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6SJ93 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6SJ93 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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