Phospholipid phosphatase-related protein type 3 (PLPPR3)
Homo sapiens — UniProt Q6T4P5
Data last refreshed: (UniProt release unknown)
Key facts
Phospholipid phosphatase-related protein type 3 (PLPPR3) is a protein from Homo sapiens identified by UniProt accession Q6T4P5, 718 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q6T4P5; gene symbol PLPPR3.
- Organism: Homo sapiens.
- Length: 718 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, hemoglobin measurement and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phospholipid phosphatase-related protein type 3 |
|---|---|
| UniProt accession | Q6T4P5 |
| Gene | PLPPR3 |
| Organism | Homo sapiens |
| Length | 718 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.38
- hemoglobin measurement · score 0.35
- reticulocyte measurement · score 0.32
- erythrocyte count · score 0.30
- bone quantitative ultrasound measurement · score 0.28
- reticulocyte count · score 0.26
- blood urea nitrogen measurement · score 0.25
- HbA1c measurement · score 0.23
- blood phosphate measurement · score 0.19
- red blood cell density measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6T4P5-F1 | alphafold | PREDICTED | 58.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6T4P5.
Amino-acid sequence (718 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLPPR3?
The strongest Open Targets associations for PLPPR3 are heel bone mineral density, hemoglobin measurement, reticulocyte measurement, erythrocyte count and bone quantitative ultrasound measurement.
How long is the PLPPR3 protein?
The Homo sapiens PLPPR3 protein (UniProt Q6T4P5) is 718 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6T4P5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6T4P5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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