Membrane progestin receptor delta (PAQR6)
Homo sapiens — UniProt Q6TCH4
Data last refreshed: (UniProt release unknown)
Key facts
Membrane progestin receptor delta (PAQR6) is a protein from Homo sapiens identified by UniProt accession Q6TCH4, 344 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q6TCH4; gene symbol PAQR6.
- Organism: Homo sapiens.
- Length: 344 amino acids.
- Top disease associations (Open Targets): calcium oxalate urolithiasis, nephrolithiasis susceptibility caused by SLC26A1 and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Membrane progestin receptor delta |
|---|---|
| UniProt accession | Q6TCH4 |
| Gene | PAQR6 |
| Organism | Homo sapiens |
| Length | 344 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- calcium oxalate urolithiasis · score 0.33
- nephrolithiasis susceptibility caused by SLC26A1 · score 0.33
- neurodegenerative disease · score 0.29
- serum albumin measurement · score 0.19
- basophil count · score 0.17
- monocyte count · score 0.13
- basophil percentage of leukocytes · score 0.11
- Red cell distribution width · score 0.09
- triglyceride measurement · score 0.06
- body fat percentage · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6TCH4-F1 | alphafold | PREDICTED | 90.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6TCH4.
Amino-acid sequence (344 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAQR6?
The strongest Open Targets associations for PAQR6 are calcium oxalate urolithiasis, nephrolithiasis susceptibility caused by SLC26A1, neurodegenerative disease, serum albumin measurement and basophil count.
How long is the PAQR6 protein?
The Homo sapiens PAQR6 protein (UniProt Q6TCH4) is 344 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6TCH4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6TCH4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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