Progestin and adipoQ receptor family member 3 (PAQR3)
Homo sapiens — UniProt Q6TCH7
Data last refreshed: (UniProt release unknown)
Key facts
Progestin and adipoQ receptor family member 3 (PAQR3) is a protein from Homo sapiens identified by UniProt accession Q6TCH7, 311 residues long. MolForge cross-references it against 0 known binders and 108 disease associations.
- UniProt accession: Q6TCH7; gene symbol PAQR3.
- Organism: Homo sapiens.
- Length: 311 amino acids.
- Top disease associations (Open Targets): reticulocyte count, Red cell distribution width and Immature Reticulocyte Fraction Measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Progestin and adipoQ receptor family member 3 |
|---|---|
| UniProt accession | Q6TCH7 |
| Gene | PAQR3 |
| Organism | Homo sapiens |
| Length | 311 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (108)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.44
- Red cell distribution width · score 0.37
- Immature Reticulocyte Fraction Measurement · score 0.30
- glioblastoma multiforme · score 0.30
- breast adenocarcinoma · score 0.29
- mean corpuscular volume · score 0.27
- reticulocyte measurement · score 0.25
- mean corpuscular hemoglobin concentration · score 0.23
- protein measurement · score 0.23
- lung adenocarcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6TCH7-F1 | alphafold | PREDICTED | 89.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6TCH7.
Amino-acid sequence (311 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAQR3?
The strongest Open Targets associations for PAQR3 are reticulocyte count, Red cell distribution width, Immature Reticulocyte Fraction Measurement, glioblastoma multiforme and breast adenocarcinoma.
How long is the PAQR3 protein?
The Homo sapiens PAQR3 protein (UniProt Q6TCH7) is 311 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6TCH7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6TCH7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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