Dynein axonemal intermediate chain 7 (DNAI7)
Homo sapiens — UniProt Q6TDU7
Data last refreshed: (UniProt release unknown)
Key facts
Dynein axonemal intermediate chain 7 (DNAI7) is a protein from Homo sapiens identified by UniProt accession Q6TDU7, 716 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q6TDU7; gene symbol DNAI7.
- Organism: Homo sapiens.
- Length: 716 amino acids.
- Top disease associations (Open Targets): metabolite measurement, sphingomyelin measurement and lung cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dynein axonemal intermediate chain 7 |
|---|---|
| UniProt accession | Q6TDU7 |
| Gene | DNAI7 |
| Organism | Homo sapiens |
| Length | 716 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- metabolite measurement · score 0.22
- sphingomyelin measurement · score 0.10
- lung cancer · score 0.08
- neoplasm · score 0.07
- small cell lung carcinoma · score 0.07
- BAP1-related tumor predisposition syndrome · score 0.07
- urinary bladder carcinoma · score 0.06
- Li-Fraumeni syndrome · score 0.05
- Pleuropulmonary blastoma · score 0.05
- heel bone mineral density · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6TDU7-F1 | alphafold | PREDICTED | 84.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6TDU7.
Amino-acid sequence (716 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAI7?
The strongest Open Targets associations for DNAI7 are metabolite measurement, sphingomyelin measurement, lung cancer, neoplasm and small cell lung carcinoma.
How long is the DNAI7 protein?
The Homo sapiens DNAI7 protein (UniProt Q6TDU7) is 716 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6TDU7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6TDU7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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