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Coiled-coil domain-containing protein 171 (CCDC171)

Homo sapiens — UniProt Q6TFL3

Gene: CCDC171Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Coiled-coil domain-containing protein 171 (CCDC171) is a protein from Homo sapiens identified by UniProt accession Q6TFL3, 1326 residues long. MolForge cross-references it against 0 known binders and 122 disease associations.

  • UniProt accession: Q6TFL3; gene symbol CCDC171.
  • Organism: Homo sapiens.
  • Length: 1326 amino acids.
  • Top disease associations (Open Targets): body mass index, diet measurement and FEV/FVC ratio.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCoiled-coil domain-containing protein 171
UniProt accessionQ6TFL3
GeneCCDC171
OrganismHomo sapiens
Length1326 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (122)

Diseases linked to this target (Open Targets).

  • body mass index · score 0.51
  • diet measurement · score 0.46
  • FEV/FVC ratio · score 0.40
  • body fat percentage · score 0.40
  • C-reactive protein measurement · score 0.39
  • vital capacity · score 0.37
  • lean body mass · score 0.36
  • body weight · score 0.35
  • fat body mass · score 0.35
  • health study participation · score 0.34

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6TFL3-F1alphafoldPREDICTED71.22—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6TFL3.

Amino-acid sequence (1326 residues)

MNLNTSSNTG DTQRLKIASL DVKQILKNET ELDITDNLRK KLHWAKKEKL EITTKHNAEL ASYESQIAKL RSEVEKGEAL RQSLEYDLAV ARKEAGLGRR AAEERLAEAH RIQEKLCAQN SELQAKTNET EKAFQTSQQK WKEECRRFEH DLEERDNMIQ NCNREYDLLM KEKSRLEKTL QEALEKHQRE KNEMESHIRE TALEEFRLQE EQWEAERREL QFIVQEQDTA VQNMHKKVEK LETEHMDCSD LLRRQTSELE FSTQREERLR KEFEATTLRV RKLEENIEAE RAAHLESKFN SEIIQLRIRD LEGALQVEKA SQAEAVADLE IIKNEFKEVE SAYEREKHNA QESFAKLNLL EKEYFSKNKK LNEDIEEQKK VIIDLSKRLQ YNEKSCSELQ EELVMAKKHQ AFLVETCENN VKELESILDS FTVSGQWTSG IHKDKDKPPS FSVVLERLRR TLTDYQNKLE DASNEEKACN ELDSTKQKID SHTKNIKELQ DKLADVNKEL SHLHTKCADR EALISTLKVE LQNVLHCWEK EKAQAAQSES ELQKLSQAFH KDAEEKLTFL HTLYQHLVAG CVLIKQPEGM LDKFSWSELC AVLQENVDAL IADLNRANEK IRHLEYICKN KSDTMRELQQ TQEDTFTKVA EQIKAQESCW HRQKKELELQ YSELFLEVQK RAQKFQEIAE KNMEKLNHIE KSHEQLVLEN SHFKKLLSQT QREQMSLLAA CALMAGALYP LYSRSCALST QRDFLQEQVN TFELFKLEIR TLAQALSTVE EKKQEEAKMK KKTFKGLIRI FRKGVIAVLA ANRLKILGQS CASLFTWMES FKEGIGMLVC TGEPQDKHKF PKHQKEQLRC LQALSWLTSS DLLAAIISSM AELQDVIGKA DPNSRICGHL LIGAAKNSFA KLMDKISLVM ECIPLHSSRS ITYVEKDSLV QRLAHGLHKV NTLALKYGLR GHVPITKSTA SLQKQILGFT QRLHAAEVER RSLRLEVTEF KRSVNEMKKE LDKAQGLQMQ LNEFKQSKLI THEKFESACE ELNNALLREE QAQMLLNEQA QQLQELNYKL ELHSSEEADK NQTLGEAVKS LSEAKMELRR KDQSLRQLNR HLTQLEQDKR RLEENIHDAE SALRMAAKDK ECVANHMRAV ENTLHKVRDQ ISLSWSAASR NDFTLQLPKL HLETFAMEGL KGGPEVVACQ AMIKSFMDVY QLASTRIMTL EKEMTSHRSH IAALKSELHT ACLRENASLQ SIGSRDHSNL SIPSRAPLPA DTTGIGDFLP LKAELDTTYT FLKETFINTV PHALTSSHSS PVTMSANANR PTQIGL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CCDC171?

The strongest Open Targets associations for CCDC171 are body mass index, diet measurement, FEV/FVC ratio, body fat percentage and C-reactive protein measurement.

How long is the CCDC171 protein?

The Homo sapiens CCDC171 protein (UniProt Q6TFL3) is 1326 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6TFL3
GeneCCDC171
OrganismHomo sapiens
Length1326
Binders0
Diseases122
View on UniProt