Sodium-driven chloride bicarbonate exchanger (SLC4A10)
Homo sapiens — UniProt Q6U841
Data last refreshed: (UniProt release unknown)
Key facts
Sodium-driven chloride bicarbonate exchanger (SLC4A10) is a protein from Homo sapiens identified by UniProt accession Q6U841, 1118 residues long. MolForge cross-references it against 0 known binders and 136 disease associations.
- UniProt accession: Q6U841; gene symbol SLC4A10.
- Organism: Homo sapiens.
- Length: 1118 amino acids.
- Top disease associations (Open Targets): neurodevelopmental disorder with hypotonia and characteristic brain abnormalities, systolic blood pressure and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium-driven chloride bicarbonate exchanger |
|---|---|
| UniProt accession | Q6U841 |
| Gene | SLC4A10 |
| Organism | Homo sapiens |
| Length | 1118 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (136)
Diseases linked to this target (Open Targets).
- neurodevelopmental disorder with hypotonia and characteristic brain abnormalities · score 0.61
- systolic blood pressure · score 0.38
- mathematical ability · score 0.33
- smoking behavior · score 0.32
- sodium measurement · score 0.28
- hypertension · score 0.28
- Calcium channel blocker use measurement · score 0.24
- blood pressure · score 0.24
- diastolic blood pressure · score 0.24
- daytime rest measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6U841-F1 | alphafold | PREDICTED | 71.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6U841.
Amino-acid sequence (1118 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC4A10?
The strongest Open Targets associations for SLC4A10 are neurodevelopmental disorder with hypotonia and characteristic brain abnormalities, systolic blood pressure, mathematical ability, smoking behavior and sodium measurement.
How long is the SLC4A10 protein?
The Homo sapiens SLC4A10 protein (UniProt Q6U841) is 1118 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6U841 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6U841 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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