Sperm microtubule inner protein 8 (SPMIP8)
Homo sapiens — UniProt Q6URK8
Data last refreshed: (UniProt release unknown)
Key facts
Sperm microtubule inner protein 8 (SPMIP8) is a protein from Homo sapiens identified by UniProt accession Q6URK8, 216 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q6URK8; gene symbol SPMIP8.
- Organism: Homo sapiens.
- Length: 216 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, eosinophil count and eosinophil percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sperm microtubule inner protein 8 |
|---|---|
| UniProt accession | Q6URK8 |
| Gene | SPMIP8 |
| Organism | Homo sapiens |
| Length | 216 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.30
- eosinophil count · score 0.16
- eosinophil percentage of leukocytes · score 0.13
- chronic obstructive pulmonary disease · score 0.12
- protein measurement · score 0.06
- infection · score 0.05
- infect · score 0.05
- metabolite measurement · score 0.05
- Hematuria · score 0.03
- peak expiratory flow · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6URK8-F1 | alphafold | PREDICTED | 57.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6URK8.
Amino-acid sequence (216 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPMIP8?
The strongest Open Targets associations for SPMIP8 are FEV/FVC ratio, eosinophil count, eosinophil percentage of leukocytes, chronic obstructive pulmonary disease and protein measurement.
How long is the SPMIP8 protein?
The Homo sapiens SPMIP8 protein (UniProt Q6URK8) is 216 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6URK8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6URK8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.