C-type lectin domain family 2 member A (CLEC2A)
Homo sapiens — UniProt Q6UVW9
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 2 member A (CLEC2A) is a protein from Homo sapiens identified by UniProt accession Q6UVW9, 174 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q6UVW9; gene symbol CLEC2A.
- Organism: Homo sapiens.
- Length: 174 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neutrophil count and myeloid white cell count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 2 member A |
|---|---|
| UniProt accession | Q6UVW9 |
| Gene | CLEC2A |
| Organism | Homo sapiens |
| Length | 174 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- neutrophil count · score 0.12
- myeloid white cell count · score 0.09
- leukocyte count · score 0.08
- platelet crit · score 0.07
- platelet count · score 0.05
- central nervous system cancer · score 0.05
- blood protein measurement · score 0.05
- eosinophil count · score 0.04
- breast carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UVW9-F1 | alphafold | PREDICTED | 88.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UVW9.
Amino-acid sequence (174 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC2A?
The strongest Open Targets associations for CLEC2A are neurodegenerative disease, neutrophil count, myeloid white cell count, leukocyte count and platelet crit.
How long is the CLEC2A protein?
The Homo sapiens CLEC2A protein (UniProt Q6UVW9) is 174 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UVW9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UVW9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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