Cytochrome P450 20A1 (CYP20A1)
Homo sapiens — UniProt Q6UW02
Data last refreshed: (UniProt release unknown)
Key facts
Cytochrome P450 20A1 (CYP20A1) is a protein from Homo sapiens identified by UniProt accession Q6UW02, 462 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.
- UniProt accession: Q6UW02; gene symbol CYP20A1.
- Organism: Homo sapiens.
- Length: 462 amino acids.
- Top disease associations (Open Targets): body mass index, alkaline phosphatase measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytochrome P450 20A1 |
|---|---|
| UniProt accession | Q6UW02 |
| Gene | CYP20A1 |
| Organism | Homo sapiens |
| Length | 462 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (77)
Diseases linked to this target (Open Targets).
- body mass index · score 0.31
- alkaline phosphatase measurement · score 0.30
- mean corpuscular volume · score 0.26
- heel bone mineral density · score 0.22
- creatinine measurement · score 0.17
- systolic blood pressure · score 0.15
- white matter microstructure measurement · score 0.08
- mean corpuscular hemoglobin · score 0.07
- body fat percentage · score 0.07
- osteoarthritis · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UW02-F1 | alphafold | PREDICTED | 88.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UW02.
Amino-acid sequence (462 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CYP20A1?
The strongest Open Targets associations for CYP20A1 are body mass index, alkaline phosphatase measurement, mean corpuscular volume, heel bone mineral density and creatinine measurement.
How long is the CYP20A1 protein?
The Homo sapiens CYP20A1 protein (UniProt Q6UW02) is 462 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UW02 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UW02 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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