Surfactant-associated protein 2 (SFTA2)
Homo sapiens — UniProt Q6UW10
Data last refreshed: (UniProt release unknown)
Key facts
Surfactant-associated protein 2 (SFTA2) is a protein from Homo sapiens identified by UniProt accession Q6UW10, 78 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q6UW10; gene symbol SFTA2.
- Organism: Homo sapiens.
- Length: 78 amino acids.
- Top disease associations (Open Targets): insomnia measurement, coronary stenosis and psoriasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Surfactant-associated protein 2 |
|---|---|
| UniProt accession | Q6UW10 |
| Gene | SFTA2 |
| Organism | Homo sapiens |
| Length | 78 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- insomnia measurement · score 0.15
- coronary stenosis · score 0.13
- psoriasis · score 0.11
- coronary artery disease · score 0.10
- schizophrenia · score 0.07
- autism spectrum disorder · score 0.06
- esophageal squamous cell carcinoma · score 0.06
- alkaline phosphatase measurement · score 0.06
- tonsillectomy risk measurement · score 0.05
- non-small cell lung carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UW10-F1 | alphafold | PREDICTED | 66.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UW10.
Amino-acid sequence (78 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SFTA2?
The strongest Open Targets associations for SFTA2 are insomnia measurement, coronary stenosis, psoriasis, coronary artery disease and schizophrenia.
How long is the SFTA2 protein?
The Homo sapiens SFTA2 protein (UniProt Q6UW10) is 78 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UW10 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UW10 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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