Regenerating islet-derived protein 3-gamma (REG3G)
Homo sapiens — UniProt Q6UW15
Data last refreshed: (UniProt release unknown)
Key facts
Regenerating islet-derived protein 3-gamma (REG3G) is a protein from Homo sapiens identified by UniProt accession Q6UW15, 175 residues long. MolForge cross-references it against 0 known binders and 195 disease associations.
- UniProt accession: Q6UW15; gene symbol REG3G.
- Organism: Homo sapiens.
- Length: 175 amino acids.
- Top disease associations (Open Targets): blood protein measurement, lung adenocarcinoma and endometrial cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Regenerating islet-derived protein 3-gamma |
|---|---|
| UniProt accession | Q6UW15 |
| Gene | REG3G |
| Organism | Homo sapiens |
| Length | 175 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (195)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.39
- lung adenocarcinoma · score 0.18
- endometrial cancer · score 0.15
- squamous cell lung carcinoma · score 0.14
- head and neck squamous cell carcinoma · score 0.12
- MODY · score 0.11
- drug use measurement · score 0.10
- breast adenocarcinoma · score 0.10
- type 2 diabetes mellitus · score 0.08
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UW15-F1 | alphafold | PREDICTED | 89.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UW15.
Amino-acid sequence (175 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with REG3G?
The strongest Open Targets associations for REG3G are blood protein measurement, lung adenocarcinoma, endometrial cancer, squamous cell lung carcinoma and head and neck squamous cell carcinoma.
How long is the REG3G protein?
The Homo sapiens REG3G protein (UniProt Q6UW15) is 175 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UW15 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UW15 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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