Insulin growth factor-like family member 1 (IGFL1)
Homo sapiens — UniProt Q6UW32
Data last refreshed: (UniProt release unknown)
Key facts
Insulin growth factor-like family member 1 (IGFL1) is a protein from Homo sapiens identified by UniProt accession Q6UW32, 110 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q6UW32; gene symbol IGFL1.
- Organism: Homo sapiens.
- Length: 110 amino acids.
- Top disease associations (Open Targets): visual perception measurement, psoriasis and sebaceous of Jadassohn nevus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Insulin growth factor-like family member 1 |
|---|---|
| UniProt accession | Q6UW32 |
| Gene | IGFL1 |
| Organism | Homo sapiens |
| Length | 110 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- visual perception measurement · score 0.21
- psoriasis · score 0.06
- sebaceous of Jadassohn nevus · score 0.05
- actinic keratosis · score 0.05
- squamous cell carcinoma · score 0.05
- esophageal adenocarcinoma · score 0.04
- lung adenocarcinoma · score 0.02
- nonpapillary renal cell carcinoma · score 0.01
- eosinophilic esophagitis · score 0.01
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UW32-F1 | alphafold | PREDICTED | 81.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UW32.
Amino-acid sequence (110 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IGFL1?
The strongest Open Targets associations for IGFL1 are visual perception measurement, psoriasis, sebaceous of Jadassohn nevus, actinic keratosis and squamous cell carcinoma.
How long is the IGFL1 protein?
The Homo sapiens IGFL1 protein (UniProt Q6UW32) is 110 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UW32 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UW32 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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