All-trans retinoic acid-induced differentiation factor (ATRAID)
Homo sapiens — UniProt Q6UW56
Data last refreshed: (UniProt release unknown)
Key facts
All-trans retinoic acid-induced differentiation factor (ATRAID) is a protein from Homo sapiens identified by UniProt accession Q6UW56, 229 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.
- UniProt accession: Q6UW56; gene symbol ATRAID.
- Organism: Homo sapiens.
- Length: 229 amino acids.
- Top disease associations (Open Targets): early-onset non-syndromic cataract, hereditary hyperferritinemia with congenital cataracts and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | All-trans retinoic acid-induced differentiation factor |
|---|---|
| UniProt accession | Q6UW56 |
| Gene | ATRAID |
| Organism | Homo sapiens |
| Length | 229 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (96)
Diseases linked to this target (Open Targets).
- early-onset non-syndromic cataract · score 0.11
- hereditary hyperferritinemia with congenital cataracts · score 0.10
- cancer · score 0.10
- isolated ectopia lentis · score 0.09
- heart failure · score 0.09
- coronary artery disease · score 0.09
- glucose measurement · score 0.09
- atrial fibrillation · score 0.09
- body mass index · score 0.09
- stroke · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UW56-F1 | alphafold | PREDICTED | 87.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UW56.
Amino-acid sequence (229 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATRAID?
The strongest Open Targets associations for ATRAID are early-onset non-syndromic cataract, hereditary hyperferritinemia with congenital cataracts, cancer, isolated ectopia lentis and heart failure.
How long is the ATRAID protein?
The Homo sapiens ATRAID protein (UniProt Q6UW56) is 229 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UW56 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UW56 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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