Protein O-glucosyltransferase 2 (POGLUT2)
Homo sapiens — UniProt Q6UW63
Data last refreshed: (UniProt release unknown)
Key facts
Protein O-glucosyltransferase 2 (POGLUT2) is a protein from Homo sapiens identified by UniProt accession Q6UW63, 502 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q6UW63; gene symbol POGLUT2.
- Organism: Homo sapiens.
- Length: 502 amino acids.
- Top disease associations (Open Targets): C-reactive protein measurement, serum gamma-glutamyl transferase measurement and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein O-glucosyltransferase 2 |
|---|---|
| UniProt accession | Q6UW63 |
| Gene | POGLUT2 |
| Organism | Homo sapiens |
| Length | 502 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.30
- serum gamma-glutamyl transferase measurement · score 0.30
- cancer · score 0.08
- neoplasm · score 0.08
- PHF-tau measurement · score 0.07
- nonpapillary renal cell carcinoma · score 0.07
- drug use measurement · score 0.04
- head and neck squamous cell carcinoma · score 0.03
- apolipoprotein A 1 measurement · score 0.02
- esophageal squamous cell carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UW63-F1 | alphafold | PREDICTED | 92.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UW63.
Amino-acid sequence (502 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with POGLUT2?
The strongest Open Targets associations for POGLUT2 are C-reactive protein measurement, serum gamma-glutamyl transferase measurement, cancer, neoplasm and PHF-tau measurement.
How long is the POGLUT2 protein?
The Homo sapiens POGLUT2 protein (UniProt Q6UW63) is 502 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UW63 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UW63 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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