Ubiquinol-cytochrome-c reductase complex assembly factor 3 (UQCC3)
Homo sapiens — UniProt Q6UW78
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquinol-cytochrome-c reductase complex assembly factor 3 (UQCC3) is a protein from Homo sapiens identified by UniProt accession Q6UW78, 93 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q6UW78; gene symbol UQCC3.
- Organism: Homo sapiens.
- Length: 93 amino acids.
- Top disease associations (Open Targets): Isolated CoQ-cytochrome C reductase deficiency, blood protein measurement and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquinol-cytochrome-c reductase complex assembly factor 3 |
|---|---|
| UniProt accession | Q6UW78 |
| Gene | UQCC3 |
| Organism | Homo sapiens |
| Length | 93 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- Isolated CoQ-cytochrome C reductase deficiency · score 0.50
- blood protein measurement · score 0.29
- body fat percentage · score 0.11
- resting heart rate · score 0.11
- triglyceride measurement · score 0.09
- neoplasm · score 0.07
- mean corpuscular hemoglobin concentration · score 0.06
- appendicular lean mass · score 0.04
- viral disease · score 0.04
- BMI-adjusted waist-hip ratio · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UW78-F1 | alphafold | PREDICTED | 73.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UW78.
Amino-acid sequence (93 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UQCC3?
The strongest Open Targets associations for UQCC3 are Isolated CoQ-cytochrome C reductase deficiency, blood protein measurement, body fat percentage, resting heart rate and triglyceride measurement.
How long is the UQCC3 protein?
The Homo sapiens UQCC3 protein (UniProt Q6UW78) is 93 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UW78 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UW78 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.