Epigen (EPGN)
Homo sapiens — UniProt Q6UW88
Data last refreshed: (UniProt release unknown)
Key facts
Epigen (EPGN) is a protein from Homo sapiens identified by UniProt accession Q6UW88, 154 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q6UW88; gene symbol EPGN.
- Organism: Homo sapiens.
- Length: 154 amino acids.
- Top disease associations (Open Targets): cancer, response to vaccine and cytokine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Epigen |
|---|---|
| UniProt accession | Q6UW88 |
| Gene | EPGN |
| Organism | Homo sapiens |
| Length | 154 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- cancer · score 0.46
- response to vaccine · score 0.16
- cytokine measurement · score 0.16
- mortality · score 0.14
- response to allogeneic hematopoietic stem cell transplant · score 0.14
- hair color · score 0.08
- balding measurement · score 0.06
- glycoprotein storage disease · score 0.04
- Hyperlipoproteinemia type 1 · score 0.04
- psoriasis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UW88-F1 | alphafold | PREDICTED | 67.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UW88.
Amino-acid sequence (154 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EPGN?
The strongest Open Targets associations for EPGN are cancer, response to vaccine, cytokine measurement, mortality and response to allogeneic hematopoietic stem cell transplant.
How long is the EPGN protein?
The Homo sapiens EPGN protein (UniProt Q6UW88) is 154 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UW88 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UW88 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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