Serine protease 55 (PRSS55)

About Serine protease 55

Serine protease 55 (PRSS55) is a protein from Homo sapiens identified by UniProt accession Q6UWB4, 352 residues long. MolForge cross-references it against 0 known binders and 170 disease associations.

Target properties

Protein name	Serine protease 55
UniProt accession	Q6UWB4
Gene	PRSS55
Organism	Homo sapiens
Length	352 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (170)

Diseases linked to this target (Open Targets).

bone density · score 0.31
urate measurement · score 0.29
systolic blood pressure · score 0.13
neuroimaging measurement · score 0.13
diet measurement · score 0.12
hypothyroidism · score 0.12
schizophrenia · score 0.12
cortical thickness · score 0.12
cortical surface area measurement · score 0.12
white matter microstructure measurement · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UWB4-F1	alphafold	PREDICTED	75.45	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWB4.

Amino-acid sequence (352 residues)

MLLFSVLLLL SLVTGTQLGP RTPLPEAGVA ILGRARGAHR PQPPHPPSPV SECGDRSIFE GRTRYSRITG GMEAEVGEFP WQVSIQARSE PFCGGSILNK WWILTAAHCL YSEELFPEEL SVVLGTNDLT SPSMEIKEVA SIILHKDFKR ANMDNDIALL LLASPIKLDD LKVPICLPTQ PGPATWRECW VAGWGQTNAA DKNSVKTDLM KAPMVIMDWE ECSKMFPKLT KNMLCAGYKN ESYDACKGDS GGPLVCTPEP GEKWYQVGII SWGKSCGEKN TPGIYTSLVN YNLWIEKVTQ LEGRPFNAEK RRTSVKQKPM GSPVSGVPEP GSPRSWLLLC PLSHVLFRAI LY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards