SLP adapter and CSK-interacting membrane protein (SCIMP)
Homo sapiens — UniProt Q6UWF3
Data last refreshed: (UniProt release unknown)
Key facts
SLP adapter and CSK-interacting membrane protein (SCIMP) is a protein from Homo sapiens identified by UniProt accession Q6UWF3, 145 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q6UWF3; gene symbol SCIMP.
- Organism: Homo sapiens.
- Length: 145 amino acids.
- Top disease associations (Open Targets): family history of Alzheimer’s disease, Alzheimer disease and platelet component distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SLP adapter and CSK-interacting membrane protein |
|---|---|
| UniProt accession | Q6UWF3 |
| Gene | SCIMP |
| Organism | Homo sapiens |
| Length | 145 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- family history of Alzheimer’s disease · score 0.18
- Alzheimer disease · score 0.16
- platelet component distribution width · score 0.13
- head and neck malignant neoplasia · score 0.11
- Blackfan-Diamond anemia · score 0.07
- Adult-onset autosomal recessive sideroblastic anemia · score 0.05
- hemoglobin E-beta-thalassemia syndrome · score 0.05
- Rh deficiency syndrome · score 0.04
- X-linked sideroblastic anemia 1 · score 0.04
- cholesterol-ester transfer protein deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWF3-F1 | alphafold | PREDICTED | 66.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWF3.
Amino-acid sequence (145 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCIMP?
The strongest Open Targets associations for SCIMP are family history of Alzheimer’s disease, Alzheimer disease, platelet component distribution width, head and neck malignant neoplasia and Blackfan-Diamond anemia.
How long is the SCIMP protein?
The Homo sapiens SCIMP protein (UniProt Q6UWF3) is 145 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWF3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWF3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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