Protein FAM180A (FAM180A)
Homo sapiens — UniProt Q6UWF9
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM180A (FAM180A) is a protein from Homo sapiens identified by UniProt accession Q6UWF9, 173 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q6UWF9; gene symbol FAM180A.
- Organism: Homo sapiens.
- Length: 173 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, mathematical ability and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM180A |
|---|---|
| UniProt accession | Q6UWF9 |
| Gene | FAM180A |
| Organism | Homo sapiens |
| Length | 173 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.22
- mathematical ability · score 0.22
- mean corpuscular volume · score 0.10
- sitting height measurement · score 0.05
- central nervous system cancer · score 0.04
- hepatocellular carcinoma · score 0.03
- red blood cell density measurement · score 0.02
- endometrial carcinoma · score 0.01
- papillary thyroid carcinoma · score 0.01
- metopic craniosynostosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWF9-F1 | alphafold | PREDICTED | 86.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWF9.
Amino-acid sequence (173 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM180A?
The strongest Open Targets associations for FAM180A are self reported educational attainment, mathematical ability, mean corpuscular volume, sitting height measurement and central nervous system cancer.
How long is the FAM180A protein?
The Homo sapiens FAM180A protein (UniProt Q6UWF9) is 173 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWF9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWF9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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